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Buygblchemlab Methamphetamine – 99.5%+ Pure Crystal Meth HCl for Advanced Research

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Chemical & Physical Properties

Property Specification
Chemical Name (S)-(+)-Methamphetamine hydrochloride
CAS Number 51-64-9
Purity 99.5%+ (HPLC/GC-MS/NMR)
Enantiomeric Excess ≥99.8% d-isomer
Appearance Large colorless crystals (1–5 mm)
Solubility >100 mg/mL in water; 50 mg/mL in ethanol; 20 mg/mL in DMSO
Melting Point 170–175°C
Molecular Weight 185.69 g/mol
pKa 9.87 (conjugate acid)
LogP 2.07
Density 1.1 g/cm³
Refractive Index 1.52 (20°C)

Download COA → NC-METH-2025-11A Lab Report


Reagent Test Guide

Reagent Expected Reaction Adulterant Alert
Marquis Orange → Green → Blue-Black Yellow/Brown = Amphetamine
Mecke Green → Blue → Black No change = PMMA
Mandelin Orange → Green Red = Opiates
Liebermann Red → Black Purple = MDMA
Simons No reaction (secondary amine absent) Blue = MDMA/MDA
Froehde Orange → Green Brown = Levomethamphetamine

Every order includes complimentary 6-reagent kit (Marquis, Mecke, Mandelin, Liebermann, Simons, Froehde) and fentanyl test strips.


Research Handling Protocol

  1. Reconstitution:
    • Dissolve 1–10 mg/mL in 0.9% sterile saline (pH 4.5–5.5) under sterile laminar flow
    • Filter through 0.22 μm PES membrane for in vivo use
  2. Dosing Examples:
    • Rodent Hyperlocomotion: 0.5–2 mg/kg IP
    • Self-Administration: 0.03–0.1 mg/kg/infusion IV
    • In Vitro DAT Binding: 10 nM–1 μM
  3. Storage & Stability:
    • Short-term: 2–8°C, desiccated, amber vial
    • Long-term: -20°C, vacuum-sealed, stable >36 months
    • Solution: Stable 48h at 4°C; freeze aliquots at -80°C
  4. Safety & Disposal:
    • Class A fume hood, double nitrile gloves, full-face shield
    • Neutralize spills with 5% sodium bicarbonate
    • Dispose via licensed chemical waste (DEA Schedule II)

Our “Precision Protocol” PDF—included free—covers solubility charts, stability data, HPLC calibration curves, and DEA-compliant disposal guidelines.


Pharmacokinetic & Pharmacodynamic Profile

Parameter Value
Onset (IV/IP) 5–15 min
Peak Plasma 30–90 min
Half-Life 9–12 hours (CYP2D6 dependent)
Volume of Distribution 3–5 L/kg
Protein Binding ~15–20%
Metabolism Hepatic (CYP2D6 → amphetamine, 4-OH-meth)
Excretion Renal (30–50% unchanged, pH-dependent)
DAT IC₅₀ 0.1–0.3 μM
SERT IC₅₀ 10–20 μM
NET IC₅₀ 0.05–0.1 μM

Impurity Profile (Batch NC-METH-2025-11A)

Potential Impurity Detected Level Limit
N-Isopropylbenzylamine <0.01% <0.1%
Methylsulfonylmethane ND <0.05%
Ephedrine/Pseudoephedrine ND <0.05%
Caffeine ND <0.1%
Fentanyl Analogs ND <1 ppm
Amphetamine <0.02% <0.1%
4-Hydroxymethamphetamine <0.03% <0.1%

ND = Not Detected (LOD: 0.001%)


Stability & Shelf Life

Condition Stability Duration Degradation Rate
-20°C, desiccated >36 months <0.1%/year
2–8°C, light-protected >24 months <0.3%/year
25°C, ambient >12 months <1%/year
Solution (saline, pH 5) >48 hours at 4°C <2% loss
Solution (DMSO) >30 days at -20°C <1% loss

NMR & Mass Spec Data (Batch NC-METH-2025-11A)

Analysis Key Signals
¹H NMR (400 MHz, D₂O) δ 7.25–7.35 (m, 5H), 3.25 (q, 1H), 2.70 (s, 3H), 1.25 (d, 3H)
¹³C NMR δ 135.5, 129.8, 128.7, 127.2, 56.3, 33.8, 16.2
MS (ESI+) m/z 150.1 [M+H]⁺, 91.1 (benzyl), 119.1 (loss of CH₃NH₂)

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  • Authenticity Guarantee – Full refund if COA fails
  • Technical Consultation – Free protocol design from PhD chemists
  • Custom Synthesis – Deuterated (d₃-methyl), ¹⁴C-labeled, or stereoisomers
  • Analytical Services – Third-party NMR/MS validation
  • Resolution Policy – Solved in <12 hours

Limited Batch – 487 Grams Remaining

Batch NC-METH-2025-11A live now. Next synthesis: Dec 05, 2025.

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Additional information

Quantity

½ oz, oz, ¼ pound, ½ pound, 1 pound

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